"Phantasy Star Portable" is based on Phantasy Star Universe and its latest expansion, Ambition of the Illuminus. The PSP title includes an all-new story mode with added missions and a multi-player mode that supports local multiplayer cooperative play with up to four players. Two new characters have been introduced since Phantasy Star Universe: Vivienne, a CAST whom the main character teams up with throughout the story. Also new to the PSP version is Helga Neumann, a villain who is responsible for terrorist attacks in the Gurhal System.
The game also received a sequel in late 2009, called Phantasy Star Portable 2.
- Ethan Waber - Nick Tagas
- Karen Erra - Erin Beers
- Hyūga Ryght - Andrew Ceglio
- Lucaim Nav/Hiru Vol - Darren Jennings
- Alfort Tylor/No Vol/Leogini Santosa Berafort/Fulyen Curtz - David Rosenthal
- Tonnio Rhima/Vivienne - Amy Rubinate
- Helga Neumann - Aileen Casas
- Lou - Maile Sandidge
- Obel Dallgun/Izuma Rutsu - Owen Thomas
- Dr. Kanal Tomrain - David Nowlin
- Maya Shidow/Lumia Waber/Remlia Norphe - Amy Provenzano
- Kalam Ryme/Liina Sukaya - Melissa Hutchison
- Do Vol/Narrator - Roger Jackson
- Laia Martinez - Gina Tuosto